HEMATOPOIESIS AND STEM CELLS TIMP-3 recruits quiescent hematopoietic stem cells into active cell cycle and expands multipotent progenitor pool

1Division of Hematology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan; 2Center of Excellence, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan; 3Ontario Cancer Institute, University of Toronto, Toronto, ON; 4Division of Cellular Therapy, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan; 5Department of Anatomy and Neurobiology, Wakayama Medical University, Wakayama, Japan; and 6Department of Cell Differentiation, The Sakaguchi Laboratory of Developmental Biology, Keio University School of Medicine, Tokyo, Japan